masterflex+pinch+clamp
Numéro de catalogue:
(BOSSBS-0758R-A750)
Fournisseur:
Bioss
Description:
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognises single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognises larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM:
1 * 100 µl
Fournisseur:
Avantor Fluid Handling
Description:
Nonmetallic wetted parts ideal for water and mild aqueous solutions.
Fournisseur:
Avantor Fluid Handling
Description:
Chemical-resistant valves provide precise fluid control.
Fournisseur:
Avantor Fluid Handling
Description:
Make the most of your Masterflex flowmeters with these replacement parts and other accessories.
Numéro de catalogue:
(MFLX70738-90)
Fournisseur:
Avantor Fluid Handling
Description:
Adapt your motor to accept gear pump heads.
UOM:
1 * 1 ST
Fournisseur:
Avantor Fluid Handling
Description:
Nonmetallic wetted parts ideal for water and mild aqueous solutions.
Fournisseur:
Avantor Fluid Handling
Description:
Operate by computer or on your iOS or Android™ device.
Numéro de catalogue:
(MFLX75800-99)
Fournisseur:
Avantor Fluid Handling
Description:
Keep your pumps running with these quality replacement hoses.
UOM:
1 * 1 ST
Fournisseur:
Avantor Fluid Handling
Description:
Easily meter corrosive fluids or gases.
Numéro de catalogue:
(BOSSBS-7416R-CY5)
Fournisseur:
Bioss
Description:
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). These exonucleases include the family of DNA polymerases (3). DNA pol α, β, ∂, and e are involved in DNA replication and repair (4). DNA pol ∂ and DNA pol e are multisubunit enzymes, with DNA pol ∂ consisting of two subunits p125, which interacts with the sliding DNA clamp protein PCNA, and p50 (5). The nuclear-encoded DNA pol © is the only DNA polymerase required for the replication of the mitochondrial DNA (6). DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7). DNA pol œ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7416R-CY3)
Fournisseur:
Bioss
Description:
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). These exonucleases include the family of DNA polymerases (3). DNA pol α, β, ∂, and e are involved in DNA replication and repair (4). DNA pol ∂ and DNA pol e are multisubunit enzymes, with DNA pol ∂ consisting of two subunits p125, which interacts with the sliding DNA clamp protein PCNA, and p50 (5). The nuclear-encoded DNA pol © is the only DNA polymerase required for the replication of the mitochondrial DNA (6). DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7). DNA pol œ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8).
UOM:
1 * 100 µl
Numéro de catalogue:
(JUCHVL04685)
Fournisseur:
JUCHHEIM Laborgerate GmbH
Description:
Malleable iron, epoxy coated.
UOM:
1 * 1 ST
Numéro de catalogue:
(MFLX95635-13)
Fournisseur:
Avantor Fluid Handling
Description:
Resists particle entrapment and bacterial growth.
UOM:
1 * 50 Voet
Numéro de catalogue:
(229-0374)
Fournisseur:
HAMMACHER KARL
Description:
Tubing clamps made of stainless steel.
UOM:
1 * 1 ST
Fournisseur:
Avantor Fluid Handling
Description:
Easily customize strainer system to suit your application.
Fournisseur:
KARTELL
Description:
Clamps made of POM, for safe connection of standard-finish glass conical joints.
Appel de prix
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l' est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
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