Synonyms:
Arctigenin, (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone, (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
ALX350312M025
ENZOALX350312M025EA
124
EUR
InStock
ENZOALX350312M025
(-)-Arctigenin (de Arctium lappa) ≥97% (par HPLC)
(-)-Arctigenin
Lignan derivative, which shows antitumor, anti-inflammatory, immunomodulatory and neuroprotective activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic and cytotoxic properties against Hep62 cells. Antagonist for platelet activating factor and Ca²⁺. Blocks the activation of Akt (protein kinase B; PKB) induced by glucose starvation.
Colorless crystals.
Soluble in DMSO (34mg/ml, heating, sonication); sparingly soluble in water.