ALX350360G001
ALX350360G005
ENZOALX350360G001EA
94.6
EUR
InStock
ENZOALX350360G001
ENZOALX350360G005
Rotenone ≥98% (par HPLC)
Rotenone
Insecticide. Inhibitor of mitochondrial electron transport. Specifically inhibits NAD-linked substrate oxidation at the oxygen side of NADH dehydrogenase (EC50=10pmol/mg). Inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding. Can inhibit mitochondrial swelling and cytochrome c release induced by N-methyl-4-phenylpyridinium.
Synthetic. Originally isolated from Lonchocarpus sp. or Derris sp.