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Anticorps
Fournisseur:
Biotium
Description:
Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
Fournisseur:
Biotium
Description:
This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
Fournisseur:
Biotium
Description:
This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.
Fournisseur:
Biotium
Description:
LSA120 MAb is directed against a lung cell antigen. It shows a well-defined reactivity with cells of the lung lineage at all stages of maturation. Non-lung lineages are negative by immuno-histology. Although the exact identity of its antigen has yet to be determined, it has been shown to be distinct from MOC-52 and UM-A9 proteins. This MAb is useful in the identification of normal and neoplastic human lung cells.
Fournisseur:
Biotium
Description:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Numéro de catalogue:
(USBI036527-FITC)
Fournisseur:
US Biological
Description:
Anti-HEYL Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI167478)
Fournisseur:
US Biological
Description:
Anti-PLK5 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI036696-APC)
Fournisseur:
US Biological
Description:
Anti-HOXB1 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI043128-FITC)
Fournisseur:
US Biological
Description:
Anti-TOP2A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI167470)
Fournisseur:
US Biological
Description:
Anti-PLEKHA5 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI036695-FITC)
Fournisseur:
US Biological
Description:
Anti-HOXA9 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI167483)
Fournisseur:
US Biological
Description:
Anti-PRDM9 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI167471)
Fournisseur:
US Biological
Description:
Anti-PEX6 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI043128-HRP)
Fournisseur:
US Biological
Description:
Anti-TOP2A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI167479)
Fournisseur:
US Biological
Description:
Anti-BPIFA1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI167477)
Fournisseur:
US Biological
Description:
Anti-PLK1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
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