10011055-250
CAYM10011055-250EA
45.2
EUR
InStock
CAYM10011055-250
4-Phényl-1,2,3-thiadiazole ≥98%
4-Phényl-1,2,3-thiadiazole
Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolises substituted amines, CYP2E1 metabolises various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 µM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner.
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