ALX450011M100
ENZOALX450011M100EA
197
EUR
InStock
ENZOALX450011M100
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine ≥97% (par titration non aqueuse)
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
Heavy metal chelator.
A cell permeable and extremely high-affinity chelator of heavy metals, yet with low affinity for Mg²⁺ and Ca²⁺.
Lipid-soluble, crossing both natural and artificial membranes. TPEN can be used in conjunction with QUIN 2 or QUIN 2/AM to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Ion specificity is Zn²⁺>Fe²⁺>Mn²⁺>>Ca²⁺=Mg²⁺. Complex with Fe²⁺ catalyses superoxide dismutation.
Soluble in dimethyl formamide, DMSO, 100% ethanol or methanol.