Synonyms:
N-(5-Chloro-2,4-dimethoxyphenyl)-N’-(5-methyl-3-isoxazolyl)urea, 1-(5-Chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea
ALX550526M005
ENZOALX550526M005EA
217
EUR
InStock
ENZOALX550526M005
PNU-120596 ≥98% (par HPLC)
PNU-120596
Nicotinic acetylcholine receptor activator.
Type II positive allosteric modulator (PAM) of α7 neuronal nicotinic acetylcholine receptor (nAChR) (EC₅₀ = 216 nM). Shows no detectable effect on α4β2, α3β4 and α9α10 receptors.
Soluble in DMSO (50 mg/ml), slightly soluble in methanol (1 mg/ml) or acetonitrile (0.5 mg/ml).