Synonyms:
2,2-Bis(hydroxymethyl)-3-quinuclidinone, 2,2-Bis(hydroxymethyl)quinuclidin-3-one
BMLGR3330005
ENZOBMLGR3330005EA
84.7
EUR
InStock
ENZOBMLGR3330005
Prima-1 ≥98% (par CCM), solide blanc à blanc cassé
Prima-1
p53 activator.
Novel cell-permeable p53 reactivating agent. Restores sequence-specific DNA binding and the active conformation to mutant p53 (in 13 of 14 p53 mutants tested) in vitro and in living cells. Induces apoptosis in human tumor cell lines and displays antitumor activity in mice.
Soluble at 25 mg/ml in ethanol, 100% DMSO and DMF. Soluble at 10 mg/ml in water.
Attention: Product is not sterile.