Synonyms:
(S)-12-HETE, HETE
BMLH0120050
ENZOBMLH0120050EA
316
EUR
InStock
ENZOBMLH0120050
12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid 50 µg/ml dans l'éthanol ≥98% (par HPLC)
12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
Biosynthesis by platelet 12-lipoxygenase. Chemotactic and chemokinetic for PMNL2 and for vascular smooth muscle cells. Antiproliferative effect on smooth muscle cells. Second messenger in angiotensin induced aldosterone production. Induces endothelial cell retraction and tumor cell adhesion.