20700
PIER20700EA
188
EUR
InStock
PIER20700
DMS (Dimethyl suberimidate dihydrochloride), Pierce™
DMS (Dimethyl suberimidate dihydrochloride)
Thermo Scientific Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.
- Reactive groups: imidoester (both ends)
- Reactive towards: amino groups (primary amines)
- Longest of three similar imidoester crosslinkers, which include DMA, DMP and DMS
- Water-soluble
- Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
- Amidine bond retains net charge character of protein primary amine to which it reacts
- Reversible at high pH values
- Tool for study of quarternary structure of proteins
Attention: For Research Use Only. Not for use in diagnostic procedures.