Synonyms:
SMPH
22363
PIER22363EA
265
EUR
InStock
PIER22363
SMPH (Succinimidyl-6-((beta-maleimidopropionamido)hexanoate), Pierce™
SMPH (Succinimidyl-6-((beta-maleimidopropionamido)hexanoate)
Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).
- Reactive groups: NHS ester and maleimide
- Reactive towards: amino and sulfhydryl groups
- Slightly longer and more soluble than SMPB
- NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
- Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
Attention: For Research Use Only. Not for use in diagnostic procedures.