90-154
PRSI90-154EA
448
EUR
InStock
PRSI90-154
Mouse recombinant DLL4 (from HEK293 cells)
Protéines et Peptides
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signalling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.