92-218
PRSI92-218EA
343
EUR
InStock
PRSI92-218
Human recombinant TRAIL (from E. coli)
Protéines et Peptides
Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.