100-0130
STMC100-0130EA
681
EUR
InStock
STMC100-0130
StemSpan-AOF Medium
Milieux de culture cellulaire
For culture and expansion of human hematopoietic cells - 500 ml.
StemSpan™-AOF is an animal origin-free (AOF) medium that has been developed for the in vitro culture and expansion of human hematopoietic cells, when appropriate growth factors/cytokines and supplements (e.g. small molecules) are added. This allows users the flexibility to prepare medium that meets their requirements. StemSpan™-AOF contains only recombinant proteins and synthetic components, and does not contain serum or other human- or animal-derived components. StemSpan™-AOF has also demonstrated a higher capacity than other commercially available media for the expansion of both CD34⁺CD90⁺CD45RA⁻ and CD34brightCD90⁺CD45RA⁻ subsets, enriched for hematopoietic stem cells: CD34+ cells from cord blood expanded in StemSpan™-AOF for 7 days demonstrated similar or higher repopulation than uncultured cells when transplanted into sub-lethally irradiated NSG mice and measured at both short- (3 week) and long-term (20 week) engraftment timepoints. StemSpan™-AOF is manufactured under relevant cGMPs, ensuring the highest quality and consistency for reproducible results.
STEMCELL TECHNOLOGIES maintains registered drug master files for StemSpan™-AOF with the US Food and Drug Administration (FDA) and with the Japan Pharmaceuticals and Medical Devices Agency (PMDA). Request a Letter of Authorization (LOA) or StemSpan™-AOF's drug master file. Note: The FDA master file is in the process of being updated with the new format of StemSpan™-AOF: currently only the 500 ml format is referenced. Please note, StemSpan™-AOF was originally launched as StemSpan™-ACF without phenol red. This name change signifies that in addition to being animal component-free, no materials of animal or human origin are used in the manufacture of this medium or its components, to at least the secondary level of manufacturing. This medium also replaces StemSpan™-ACF.
Attention: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').