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Anticorps
Fournisseur:
Biotium
Description:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Numéro de catalogue:
(BTIUBNUM1070-50)
Fournisseur:
Biotium
Description:
This antibody recognizes a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L( )-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
UOM:
1 * 50 µl
Numéro de catalogue:
(BOSSBS-10081R-HRP)
Fournisseur:
Bioss
Description:
No data available.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11636R-FITC)
Fournisseur:
Bioss
Description:
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. Tissue specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. Similarity: Belongs to the immunoglobulin superfamily. Contactin family. Contains 4 fibronectin type-III domains. Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4106R-A647)
Fournisseur:
Bioss
Description:
FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8048R-HRP)
Fournisseur:
Bioss
Description:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
UOM:
1 * 100 µl
Numéro de catalogue:
(USBIB2553-10A-PE)
Fournisseur:
US Biological
Description:
Anti-BMP3 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIC2099-99K)
Fournisseur:
US Biological
Description:
Anti-CCR5 Rat Monoclonal Antibody [clone: HEK/1/85a]
UOM:
1 * 1 EA
Numéro de catalogue:
(USBIC2099-93T)
Fournisseur:
US Biological
Description:
Anti-CCR4 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBIC2085-52M-BIOT)
Fournisseur:
US Biological
Description:
Anti-CSNK1A1 Rabbit Polyclonal Antibody (Biotin)
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIB2553-10A-HRP)
Fournisseur:
US Biological
Description:
Anti-BMP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIB2553-11F-FITC)
Fournisseur:
US Biological
Description:
Anti-GDF10 Rabbit Polyclonal Antibody (FITC (Fluorescein))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIC2099-98G)
Fournisseur:
US Biological
Description:
Anti-CCR5 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBIA2275-85L-APC)
Fournisseur:
US Biological
Description:
Anti-APP Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBIA2275-85P-APC)
Fournisseur:
US Biological
Description:
Anti-APP Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Fournisseur:
Biotium
Description:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
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