15039-500
15039-1
15039-5
CAYM15039-500EA
55.5
EUR
InStock
CAYM15039-500
CAYM15039-1
CAYM15039-5
Thymoquinone ≥98%
Thymoquinone
The black seeds of Nigella have long been ingested to treat a broad range of diseases, including inflammation and cancer.
Thymoquinone is a natural phytochemical isolated from the seeds of N. sativa. It has anti-inflammatory effects, blocking the synthesis of leukotrienes. Thymoquinone inhibits the growth of leukemia cells (IC50 = 1,5 μg/ml), inducing apoptosis by down-regulating the expression of Bcl-2 while up-regulating Bax expression. In addition to blocking cell proliferation and triggering apoptosis, thymoquinone (15 μM) suppresses STAT3-regulated gene expression and prevents angiogenesis.