0215206410
0215206425
0215206480
ICNA0215206410EA
69.5
EUR
InStock
ICNA0215206410
ICNA0215206425
ICNA0215206480
Sodium-2-propylvalerate, poudre cristalline
Sodium-2-propylvalerate
Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3α and GSK-3β. Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400 μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells.
In animal studies, Valproic Acid has been observed to reduce tumor growth and metastasis formation. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase. This compound is also an inhibitor of the CYP2C9 enzyme.
Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.
Soluble in water (50 mg/ml) clear, colorless solution.
Attention: Research Use Only (RUO).