0219014805
0219014825
0219014880
ICNA0219014805EA
63.6
EUR
InStock
ICNA0219014805
ICNA0219014825
ICNA0219014880
Ampicilline sel de sodium
Ampicillin sodium salt
Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic.
It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as benzylpenicillin; against gram-negative bacteria, it has a similar mode of action as chloramphenicol and tetracyclines. In E. coli it inhibits cell wall synthesis.
Used to select for ampicillin resistance in mutated and transformed cells.
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: gram-negative and gram-positive bacteria.
Soluble in water (50 mg/ml); soluble in 1 M ammonium hydroxide, dilute acids or bases; practically insoluble in alcohol, chloroform, ether and fixed oils.