Synonyms:
(-)-Erythromycin
0219019701
0219019705
ICNA0219019701EA
24.4
EUR
InStock
ICNA0219019701
ICNA0219019705
Érythromycine ≥98%, en poudre
Érythromycine
Erythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of erythromycins B and C.
Used in cell culture applications at approximately 100 mg/liter. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth.
Mode of Action: Inhibits protein synthesis (elongation) at the level of transpeptidation (aminoacyl translocation A-site to P-site).
Antimicrobial spectrum: Gram-negative and gram-positive bacteria.
Slightly soluble in water (~2 mg/ml); moderately soluble in ether, ethylene dichloride, amyl acetate; freely soluble in alcohols (ethanol - 50 mg/ml), acetone, chloroform, acetonitrile, ethyl acetate. Soluble in 2 M Hydrochloric acid (50 mg/ml).