0219547310
0219547325
0219547380
ICNA0219547310EA
35.1
EUR
InStock
ICNA0219547310
ICNA0219547325
ICNA0219547380
Pyrazinamide ≥99%, poudre blanche
Pyrazinamide
Pyrazinamide is used therapeutically as an antitubercular agent.
Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention and mechanisms of resistance.
The active moiety of pyrazinamide is pyrazinoic acid (POA). POA is thought to disrupt membrane energetics and inhibit membrane transport function at acid pH in Mycobacterium tuberculosis. Iron enhances the antituberculous activity of pyrazinamide. Pyrazinamide and its analogs have been shown to inhibit the activity of purified FAS I.
Soluble in water (50 mg/ml - clear).