0215670983
0215670980
ICNA0215670983EA
118
EUR
InStock
ICNA0215670983
ICNA0215670980
Sulphamethazine sodium salt, poudre blanche
Sulphamethazine sodium salt
Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.
- Presentation: White Powder
- H2O: soluble (50 mg/mL)
- Storage temperature: Store at +4 °C.
Storage temperature.: +4 °C