15427-10
15427-5
15427-1
15427-50
CAYM15427-10EA
609
EUR
InStock
CAYM15427-10
CAYM15427-5
CAYM15427-1
CAYM15427-50
Apixaban ≥98%, solide cristallin
Apixaban
Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM).
In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model of aortic heterotopic valve replacement. Formulations containing apixaban have been used to prevent blood clot formation in patients with atrial fibrillation.