Synonyms:
PMSF, Phenylmethanesulphonyl fluoride, Phenylmethylsulphonyl fluoride, α-Toluenesulphonyl fluoride
02195381.2
0219538180
0219538101
0219538105
0219538125
ICNA02195381.2EA
25
EUR
InStock
ICNA02195381.2
ICNA0219538180
ICNA0219538101
ICNA0219538105
ICNA0219538125
α-Toluenesulfonyle fluorure, cristaux aiguilles blancs à blanc cassé
α-Toluenesulfonyle fluorure
Phenylmethylsulfonyl fluoride is an irreversible inhibitor of serine proteases - inhibits trypsin, chymotrypsin and protease. Inhibits mammalian acetyl cholinesterase, but not those from fish sources.
- Presentation: White to off white needle crystals
- Causes sulfonylation of the active-site serine residue
- A less toxic substitute for the extremely toxic diisopropylfluorophosphate
Phenylmethylsulfonyl fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase.
Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.
Soluble in methanol and ethanol