Synonyms:
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide, 2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide, IKK2 Inhibitor IV
15115-10
15115-1
15115-5
15115-500
CAYM15115-10EA
345
EUR
InStock
CAYM15115-10
CAYM15115-1
CAYM15115-5
CAYM15115-500
TPCA-1 ≥98%
TPCA-1
- A selective inhibitor of IKK2
A selective inhibitor of IKK2 (IC₅₀s = 17,9 nM and 0,40 μM for IKK2 and IKK1, respectively); reduces the severity and onset of collagen-induced arthritis in mice and blocks cytokine release in an antigen-driven rat model of lung inflammation.