M-Clarity™ quality level = MQ200
F6627-1G
F6627-10G
F6627-5G
F6627-1GEA
30.6
EUR
InStock
F6627-1G
F6627-10G
F6627-5G
5-Fluorouracile ≥99% (par HPLC), en poudre, Sigma-Aldrich®
5-Fluorouracile
5-Fluorouracil has been used to induce apoptosis in cells. It has been used as a chemosensitising agent. A potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase, thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.