BMLLP1080001
BMLLP1080005
ENZOBMLLP1080001EA
156.2
EUR
InStock
ENZOBMLLP1080001
ENZOBMLLP1080005
N-Palmitoyl phosphatidylethanolamine ≥98% (par CCM), solide blanc
N-Palmitoyl phosphatidylethanolamine
Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice (100 mg/kg, i.p.), without causing taste aversion. Has been found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations). This suggests that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight.
Soluble in 100% ethanol (2 mg/ml with ~30 minutes sonication at 37 °C) or dimethylacetamide (1 mg/ml with ~30 minutes sonication at 37 °C).