Synonyms:
Monophosphoryl Lipid A
ALX581203L001
ALX581203R500
ENZOALX581203L001EA
591
EUR
InStock
ENZOALX581203L001
ENZOALX581203R500
MPLA (de E.coli) ≥99.9% serotype R515 (Re), TLRgrade™ prêt-à-l'emploi
MPLA
TLR4 activator.
Isolated from E. coli, Serotype R515 (Re mutant). Prepared by acid hydrolysis from purified E. coli, Serotype R515 (Re) LPS (isolated by a modification of the PCP extraction method), converted to the uniform salt form.
Activates TLR4 (Toll-like receptor 4). Does not activate TLR2 as determined with splenocytes and macrophages from TLR4 deficient mice. Exhibits reduced endotoxic and pyrogenic activity compared to lipid A and LPS.