0219004094
0219004025
0219004080
0219004090
0219004091
ICNA0219004094EA
967
EUR
InStock
ICNA0219004094
ICNA0219004025
ICNA0219004080
ICNA0219004090
ICNA0219004091
Dexamethasone, poudre blanche
Dexamethasone
Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin).
It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils.
Dexamethasone is a glucocorticoid anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. It also inhibits the induction of nitric oxide synthase.
Slightly soluble in water (10 mg/100 ml), ethanol (1 mg/ml), chloroform; sparingly soluble in acetone, alcohol, dioxane, and methanol; very slightly soluble in ether