0219521310
0219521325
0219521380
0219521383
0219521390
0219521391
ICNA0219521310EA
36
EUR
InStock
ICNA0219521310
ICNA0219521325
ICNA0219521380
ICNA0219521383
ICNA0219521390
ICNA0219521391
Guanosine 5'-triphosphate disodium salt ≥95%, poudre blanche
Guanosine 5'-triphosphate disodium salt
Guanosine-5'-triphosphate, a purine nucleotide is required as a coenzyme for protein biosynthesis in a cell-free system.
Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.