Synonyms:
5-(1,2-Dithiolan-3-yl)pentanoic acid, (±)-1,2-Dithiolane-3-pentanoic acid, 5-(1,2)Dithiolan-3-yl-pentanoic acid, DL-α-Lipoic acid, DL-Thioctic acid (oxidized), DL-6,8-Thioctic acid, Lip(S2), 6,8-Dithiooctanoic acid
0210113825
0210113801
0210113805
0210113850
ICNA0210113825EA
299
EUR
InStock
ICNA0210113825
ICNA0210113801
ICNA0210113805
ICNA0210113850
(±)-Acide 5-(dithiolanne-3-yl)valerique ≥98%, en poudre
(±)-Acide 5-(dithiolanne-3-yl)valerique
DL-Thioctic Acid is a hydrogen transferrin cofactor.
Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages.
Soluble in fat solvents, methanol (50 mg/ml - clear pale yellow solution), ethanol(50 mg/ml - clear solution); practically insoluble in water.