NUCLEODUR® C18 ec is a medium density monomeric octadecyl modified silica phase for HPLC.
- High purity spherical silica gel
- Hydrophobic, endcapped phase for RP chromatography
- Separation mechanism based on hydrophobic interactions
The phase shows an excellent selectivity with comparable retention pattern as the most common RP phases. Thus, it is an ideal alternative for a replacement of any standard RP phase.
It has wide recommended applications such as analysis of basic, neutral or acidic drugs, derivatised amino acids, pesticides, fat-soluble vitamins, aldehydes and ketones, as well as phenolic compounds.
The wide pore RP phase (300 Å) is ideal for separations of biomolecules like proteins or peptides.
EC guard columns are used for analytical EC columns with the Column Protection System guard column holder (554-5851).
VP guard columns are used for preparative VarioPrep columns with the following guard column holders:
8,0×10 mm (Int.Ø×L) guard column for 8,0 and 10,0 mm (Int.Ø) preparative column with holder MANA718251.
16,0×10 mm (Int.Ø×L) guard column for 16,0 and 21,0 mm (Int.Ø) preparative column with holder MANA718256.
32,0×15 mm (Int.Ø×L) guard column for 32,0 and 40,0 mm (Int.Ø) preparative column with holder MANA718253.
50,0×15 mm (Int.Ø×L) guard column for ≥50,0 mm (Int.Ø) preparative column with holder MANA718255.