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Numéro de catalogue: (BOSSBS-4898R-A647)

Fournisseur:  Bioss
Description:   Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances oestrogen-dependent transactivation mediated by oestrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2035R-A750)

Fournisseur:  Bioss
Description:   Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.
UOM:  1 * 100 µl
Fournisseur:  VWR Collection
Description:   Les thermocycleurs PCR de la famille XT de VWR® associent l’innovation industrielle à celle de nos retours clients, pour concevoir des appareils robustes qui intègrent une ventilation silencieuse et qui s’adaptent à n’importe quelle paillasse. Le bloc de 96 puits à fonctionnement rapide est contrôlé par 8 éléments Peltier, qui permettent d’obtenir des résultats PCR reproductibles et d’offrir une option de PCR par gradient.
Grâce à une technologie avancée, les thermocycleurs XT peuvent être connectés à distance via un câble Ethernet et être contrôlés par un thermocycleur XT maître⁹⁶ un PC ou un appareil mobile (smartphone/tablette).
Le logiciel et l'application nécessaires sont gratuits et offrent la même interface utilisateur intuitive que l'écran tactile TFT 7" de haute précision dont le thermocycleur XT⁹⁶ est équipé.
Lorsqu'il est utilisé dans le cadre d'une configuration de contrôle à distance, l'XTender⁹⁶ constitue une unité secondaire parfaite, ne disposant pas d'écran intégré mais ramenée à sa fonction première de fournir d'excellents résultats PCR, tout en réduisant les coûts et des ressources précieuses.
Autres caractéristiques innovantes:
Promotion
Fournisseur:  Metro International
Description:   The open wire design of these heavy-gauge shelves minimizes dust accumulation and allows a free circulation of air, greater visibility of stored items and greater light penetration.
Promotion
Numéro de catalogue: (444-0344)

Fournisseur:  GRANT INSTRUMENTS
Description:   Plateforme plate avec tapis de caoutchouc antidérapant pour boîtes de Petri, flacons de culture, L×P : 219×219 mm
UOM:  1 * 1 ST
Fournisseur:  HYSERVE GMBH & CO. KG
Description:   Easy Plate are ready-to-use culture media prepared in an easy-to-use, stackable film plate format that saves space, reduces waste, eliminates preparation time and labor, and streamlines your test procedures.

Fournisseur:  2MAG
Description:   Systèmes d'agitation ultra-plats pour un mélange précautionneux des cultures cellulaires. Adaptés aux flacons de culture avec systèmes d'agitateurs et de billes de rotation. Le boîtier en acier inoxydable fermé hermétiquement est étanche à l'eau, résistant aux poussières et aux germes. Températures de fonctionnement jusqu'à 50 °C.
UOM:  1 * 1 ST
Numéro de catalogue: (BOSSBS-4898R-CY5.5)

Fournisseur:  Bioss
Description:   Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-4898R-A555)

Fournisseur:  Bioss
Description:   Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0251R-A488)

Fournisseur:  Bioss
Description:   Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0251R-A555)

Fournisseur:  Bioss
Description:   Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
UOM:  1 * 100 µl
Fournisseur:  Heidolph Instruments GmbH & Co.KG
Description:   Pour un mélange vigoureux des microplaques de titrage. L'amplitude de vibration de 1,5 mm garantit l'absence d'éclaboussures, même avec des récipients pleins ; celle de 3 mm assure des résultats de mélange optimaux, même en quantités infimes. Les agitateurs conçus pour une utilisation continue sont équipés d'une protection anti-surchauffe et d'une plate-forme isolée pour une accumulation de chaleur quasi nulle.
Numéro de catalogue: (GREI653081_100)

Fournisseur:  Greiner Bio-One
Description:   Coverglass for Terasaki plates
UOM:  1 * 100 ST
Fournisseur:  Thermo Fisher Scientific
Description:   Base plate for HyperSep-96 well plate, Pour: HyperSep 96 well plates
Numéro de catalogue: (METO1824DRC)

Fournisseur:  Metro International
Description:   The heavy-duty dunnage shelves enhance the weight bearing capacity the system.
UOM:  1 * 1 ST
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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