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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI77-100)
Fournisseur:
ProSci Inc.
Description:
The JC12 monoclonal antibody specifically reacts with human Foxp1, a winged helix transcription factor that is expressed in almost all human tissue. In several tumor types, the gene is lost suggesting it plays a tumor suppressive role. It plays an important role in the development of the brain, lungs, thymus, and heart. Foxp1 is also involved in the development of early B cells.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI31-153)
Fournisseur:
ProSci Inc.
Description:
GLI1 is a protein which is a member of the Kruppel family of zinc finger proteins. The function of this gene has not been determined; however, it may play a role in normal development gene transcription. Mouse mutation studies indicate possible involvement in human foregut malformation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-005)
Fournisseur:
ProSci Inc.
Description:
The exact function of C2orf28 remains unknown.This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 50 µG
Fournisseur:
TOSOH Bioscience
Description:
Anion exchange resins are polymer-based media developed for the separation of biomolecules including monoclonal antibodies and oligonucleotides. Several of these resins are available in multiple particle sizes allowing for their use in capture, intermediate purification or polishing process steps.
Fournisseur:
GLASWARENFABRIK KARL HECHT
Description:
Blood sedimentation pipettes for the macro method.
Numéro de catalogue:
(PRSI5467)
Fournisseur:
ProSci Inc.
Description:
SLAIN1 Antibody: SLAIN1 is a novel stem cell protein that was identified by transciptional profiling of mouse and human embryonic stem cells (ESCs) and is expressed at the stem cell and epiblast stages. Unlike its more widely expressed homolog SLAIN2, SLAIN1 was found to be expressed in the epiblast, nervous system, tailbud and somites of the developing mouse embryo later experiments suggested that SLAIN1 may play a role in the development of the nervous system as well as in the morphogenesis of several embryonic structures.
UOM:
1 * 1 EA
Fournisseur:
Genscript
Description:
Efficient and gentle cell separation based on surface markers is essential for researching specific cell populations, and for developing life-saving cell and gene therapies. GenScript has renowned expertise in developing magnetic bead products for bioseparation of various types of biomolecules. The CytoSinct™ Cell Separation Technology uses perfected nanoparticle empowered immunomagnetic separation technology to isolate specific cell populations of interest, combining the specificity and sensitivity of antibody-based purification with the gentleness of nanoparticles and the ease and speed of magnetic separation.
Numéro de catalogue:
(PRSI5639)
Fournisseur:
ProSci Inc.
Description:
CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
UOM:
1 * 1 EA
Fournisseur:
Industrial Physics
Description:
These roughness scales are designed to estimate the surface roughness, at touch or sight, specifically developed for the profiles related to the condition of ships propellers over life.
Numéro de catalogue:
(PRSI26-033)
Fournisseur:
ProSci Inc.
Description:
DSCAM is a cell adhesion molecule that can mediate cation-independent homophilic binding activity. DSCAM could be involved in nervous system development.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-756)
Fournisseur:
ProSci Inc.
Description:
The down-regulation of C9orf127 may be closely associated with tumorigenesis and metastasis of colorectal carcinoma. However, it may not contribute to the development and progression of gastric carcinoma.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI55-999)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.
UOM:
1 * 400 µl
New Product
Fournisseur:
Shenandoah Biotechnology
Description:
Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Numéro de catalogue:
(PRSI32-237)
Fournisseur:
ProSci Inc.
Description:
ZAP70(zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Zap70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the zap-70 gene. ZAP-70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5633)
Fournisseur:
ProSci Inc.
Description:
DCLK1 Antibody: DCLK1 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK1 mRNA, like that of the homologous DCLK2 and DCLK3, is highly expressed in adult brain, but only DCLK1 and DCLK2 transcripts are present in human fetal brain and the developing mouse embryo, suggesting that DCLK1 and DCLK2 may play roles in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a gene that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization. Unlike DCLK1, DCLK2 expression does not change in DCX-null mice.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4629)
Fournisseur:
ProSci Inc.
Description:
SATB2 Antibody: Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development.
UOM:
1 * 1 EA
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