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Numéro de catalogue: (PRSIXP-5125BT)

Fournisseur:  ProSci Inc.
Description:   Eotaxin is a 74 amino acid, eosinophil chemotactic CC chemokine originally found in bronchoalveolar lavage fluid from allergic inflammatory subjects. It is involved in regulating the recruitment and activation of inflammatory leukocytes, particularly eosinophils. Eotaxin binds and activates the CCR3 chemokine receptor, and may play a fundamental role in the development of allergic responses.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI56-184)

Fournisseur:  ProSci Inc.
Description:   In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI6453)

Fournisseur:  ProSci Inc.
Description:   TMEM147 Antibody: TMEM147 is a recently identified protein that associates with Nicalin and NOMO, forming a complex that is thought to be similar to the gamma-secretase complex. TMEM147 localizes to the endoplasmic reticulum (ER), and in zebrafish, is expressed during early development. TMEM147 also interacts with the M3 muscarinic receptor (M3R) in the ER and is thought to negatively its expression and function.
UOM:  1 * 1 EA
Numéro de catalogue: (181-0300)

Fournisseur:  NRG DEVELOPMENTS LTD
Description:   Pompe pour conteneur, Adaptateur Tri-Sure pour pompe de 205 litres
UOM:  1 * 1 ST
Numéro de catalogue: (PRSI55-852)

Fournisseur:  ProSci Inc.
Description:   This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI40-607)

Fournisseur:  ProSci Inc.
Description:   PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids).
UOM:  1 * 1 EA
Numéro de catalogue: (HUBE3045.0003.98)

Fournisseur:  HUBER
Description:   The CT50 Single OLÉ cold trap means that evaporation tasks in the laboratory are now even easier and cheaper. It has been specially developed to offer highly efficient solvent recovery in laboratory conditions.
UOM:  1 * 1 ST
New Product
Fournisseur:  ProSci Inc.
Description:   The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.
UOM:  1 * 0,025 mg
New Product
Numéro de catalogue: (PRSIXP-5111BT)

Fournisseur:  ProSci Inc.
Description:   BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI38-136)

Fournisseur:  ProSci Inc.
Description:   BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair.
UOM:  1 * 50 µG
Numéro de catalogue: (STMC100-1402)

Fournisseur:  STEMCELL Technologies
Description:   Stimulating T cells with HHV6 (U90) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HHV6 (U90) Peptide pool is a lyophilised mixture of 267 peptides from protein U90 of human herpesvirus 6B (HHV-6B; strain Z29) and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 1078 on U90. U89 - U90 RNA expression occurs under immediate-early conditions of infection (Mirandola <i>et al.</i>), and the associated protein exhibits peri-nuclear and cytoplasmic localization (Nikolaou <i>et al.</i>). Also known as immediate-early protein IE1, latency-associated transcripts of HHV6 may function as a source of IE1 during viral reactivation (Kondo <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:  1 * 1 PE
New Product
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Numéro de catalogue: (PRSI27-917)

Fournisseur:  ProSci Inc.
Description:   ZIon Channel5 is a member of the ZIon Channel family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. This gene encodes a protein of unknown function.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI92-714)

Fournisseur:  ProSci Inc.
Description:   Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signalling in osteoblastic cells.
UOM:  1 * 50 µG
Numéro de catalogue: (USBI126559)

Fournisseur:  US Biological
Description:   Anti-FABP7 Rabbit Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI7229)

Fournisseur:  ProSci Inc.
Description:   GRIP1 Antibody: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI7529)

Fournisseur:  ProSci Inc.
Description:   BHLHA15 (basic helix-loop-helix protein 15), also known as MIST1 (muscle intestine and stomach expression 1) belongs to the bHLH family of transcription factors and plays a role in regulating the transcriptional activity of MYOD1 in muscle cell development as well as serving as a key regulator of acinar cell function (1,2). BHLHA15 contains a basic helix-loop-helix (bHLH) domain and is capable of binding to E-box motifs as a homodimer or a heterodimer with E-proteins. It may also negatively regulate bHLH-mediated transcription through a N-terminal repressor domain. It is expressed in mammary epithelial cells and is essential for the regulation of mammary gland development.
UOM:  1 * 1 EA
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