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Ace+Method+Development+Kits
Fournisseur:
Thermo Fisher Scientific
Description:
These reversed phase columns were developed in conjunction with the Vanquish™ UHPLC system to take advantage of the system's extended pressure capabilities and robustness. The result is a new level of separation, speed and throughput that solve analytical challenges of analysing complex matrices using liquid chromatography and LC-MS.
Fournisseur:
STEMCELL Technologies
Description:
Insulin-like growth factor 2 (IGF-II) is a polypeptide that belongs to the family of insulin-like growth factors that are similar in molecular structure to proinsulin. IGF-II binding to IGF-I receptor activates a signaling cascade via the MAPK and PI3K pathways. IGF-II affects growth, differentiation, and survival of cells in a variety of tissues during embryonic development. It stimulates proliferation and migration of primary lymphatic endothelial cells, and induces lymphangiogenesis (Guvakova).
Numéro de catalogue:
(AATB23070)
Fournisseur:
AAT BIOQUEST INC
Description:
Congo Red has been used as a common qualitative staining method for the identification of amyloids in vitro and in tissue sections.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(HACHLXV4169920001)
Fournisseur:
Hach
Description:
Immersion or flow-through probe with optical luminescence measuring method. The luminescence method means the measurement is unaffected by any type of interference. The sensor features PROGNOSYS which is a predictive diagnostic system that allows users to be proactive in their maintenance, by alerting them to upcoming instrument issues.
UOM:
1 * 1 ST
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.
Numéro de catalogue:
(PRSI26-024)
Fournisseur:
ProSci Inc.
Description:
LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-454)
Fournisseur:
ProSci Inc.
Description:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.HOXA2 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiateon. HOXA2 may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-140)
Fournisseur:
ProSci Inc.
Description:
SOX13 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Fournisseur:
LGC Standards PROMOCHEM
Description:
This solution is intended for use as a certified reference material in the determination of water in motor oil by Karl Fischer titration.
Fournisseur:
STEMCELL Technologies
Description:
Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitor cells to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux and Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of the placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam and Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam and Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>).
Numéro de catalogue:
(AATB17011)
Fournisseur:
AAT BIOQUEST INC
Description:
The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.
UOM:
1 * 25 Nmo
New Product
Numéro de catalogue:
(PRSI76-788)
Fournisseur:
ProSci Inc.
Description:
The HIB19 monoclonal antibody specifically reacts with human CD19, a 95 kDa type 1 transmembrane glycoprotein also known as B4. It is expressed on all stages of B cell development except for final plasma cells and on follicular dendritic cells. CD19 plays a role in B cell proliferation, activation, and differentiation. It functions as a BCR co-receptor with CD21 and CD81.
UOM:
1 * 1 EA
New Product
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