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Ace+Method+Development+Kits
Numéro de catalogue:
(BOSSBS-4264R-A750)
Fournisseur:
Bioss
Description:
May regulate transcription during sexual development.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0231R-CY3)
Fournisseur:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.
UOM:
1 * 100 µl
Fournisseur:
Merck
Description:
di-Sodium tétraborate décahydraté ACS, ISO, Reag. Ph. Eur. pour analyses, Supelco®
Numéro de catalogue:
(BOSSBS-0200R-A680)
Fournisseur:
Bioss
Description:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
UOM:
1 * 100 µl
Fournisseur:
Merck
Description:
Histosec® pastilles (without DMSO) is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available with the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.
Fournisseur:
Avantor
Description:
Avantor® ACE® Excel® SuperC18 columns provide high stability across an extended pH range. These stainless steel columns are ideal for use with LC/MS compatible buffers and can be used with both MeOH and MeCN mobile phases.
Fournisseur:
Merck
Description:
Manganèse (II) chlorure tétrahydraté, EMSURE® ACS pour analyses, Supelco®
Numéro de catalogue:
(BOSSBS-3205R-CY5.5)
Fournisseur:
Bioss
Description:
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15570R-CY3)
Fournisseur:
Bioss
Description:
IGFL1 belongs to the insulin-like growth factor (IGF) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15570R-CY5)
Fournisseur:
Bioss
Description:
IGFL1 belongs to the insulin-like growth factor (IGF) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15570R-A350)
Fournisseur:
Bioss
Description:
IGFL1 belongs to the insulin-like growth factor (IGF) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7065R-CY5)
Fournisseur:
Bioss
Description:
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11833R-CY5)
Fournisseur:
Bioss
Description:
Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0075R-CY7)
Fournisseur:
Bioss
Description:
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity).
UOM:
1 * 100 µl
Fournisseur:
Merck
Description:
Les solvants EMSURE® sont adaptés à un large éventail d'applications classiques de laboratoire et sont fréquemment utilisés pour des applications réglementées et hautement exigeantes. EMSURE® fournit les meilleures spécifications de produit dans le monde entier. Nous déclarons que notre gamme EMSURE® est conforme à l'ACS, avec la partie réactif de la Pharmacopée européenne (Reag. Ph. Eur.) et aussi avec les normes ISO.
Fournisseur:
Avantor
Description:
Ammonium sulfate 99.0-100.5%, granuleux FCC, ACS, J.T.Baker®
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