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Numéro de catalogue: (PRSI25-211)

Fournisseur:  ProSci Inc.
Description:   SCML4 is a putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI55-104)

Fournisseur:  ProSci Inc.
Description:   CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
UOM:  1 * 400 µl
New Product
Fournisseur:  MIELE
Description:   Les laveurs/désinfecteurs Miele représentent une solution professionnelle pour la verrerie de laboratoire destinée aux analyses. Cette approche est particulièrement délicate pour les matériaux. Elle est recommandée par les plus grands fabricants de verrerie de laboratoire.
Numéro de catalogue: (BOSSBS-8381R-A488)

Fournisseur:  Bioss
Description:   Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-9623R-CY7)

Fournisseur:  Bioss
Description:   Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.
UOM:  1 * 100 µl
Numéro de catalogue: (PRSI55-234)

Fournisseur:  ProSci Inc.
Description:   Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity). Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity).
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI25-466)

Fournisseur:  ProSci Inc.
Description:   FOXI1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOXI1 may plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis.This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene.
UOM:  1 * 50 µG
Numéro de catalogue: (TAAGTGG0001)

Fournisseur:  KREGLINGER EUROPE
Description:   Nutrient-rich dehydrated culture media. It contains selected growth factors and nutritional requirements optimised to promote bacterial development.
UOM:  1 * 1 ST
Numéro de catalogue: (PRSI25-123)

Fournisseur:  ProSci Inc.
Description:   NKX3-2 is a member of the NK family of homeobox-containing proteins. It may play a role in skeletal development. This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI27-650)

Fournisseur:  ProSci Inc.
Description:   HMX1 acts as a transcriptional antagonist and is part of the Hmx family of homeodomain proteins which are predominately expressed in discrete regions of developing sensory tissues.
UOM:  1 * 50 µG
Fournisseur:  OZ BIOSCIENCES
Description:   These magnetic sets have been developped for efficient in vivo transfection or transduction with <i>in vivo</i> Magnetofection technology.
Numéro de catalogue: (PRSI29-740)

Fournisseur:  ProSci Inc.
Description:   When FAM107A is transfected into cell lines in which it is not expressed, it suppresses cell growth. It may play a role in tumor development.
UOM:  1 * 1 EA
Numéro de catalogue: (AATB72863)

Fournisseur:  AAT BIOQUEST INC
Description:   FastClick™ 6-TAMRA Alkyne contains both the moiety of FastClick (for assisting click efficiency) and 6-TAMRA fluorophore (as the fluorescence tag) for developing 6-TAMRA-based fluorescent probes.
UOM:  1 * 1 mg
New Product
Numéro de catalogue: (PRSI55-655)

Fournisseur:  ProSci Inc.
Description:   Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
UOM:  1 * 400 µl
New Product
Numéro de catalogue: (PRSI4691)

Fournisseur:  ProSci Inc.
Description:   GDF6 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.
UOM:  1 * 1 EA
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