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Chem-Durance®+Bio+Precision+Pump+Tubing
Numéro de catalogue:
(BOSSBS-12549R-A680)
Fournisseur:
Bioss
Description:
Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (AH) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function. The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts. The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21.
UOM:
1 * 100 µl
Numéro de catalogue:
(USBI029832)
Fournisseur:
US Biological
Description:
Anti-CXCL10 Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Fournisseur:
Bertin Instruments
Description:
Échantillonneur d'air à sec portable pour le contrôle de la contamination biologique.
Numéro de catalogue:
(BOSSBS-13070R-CY5)
Fournisseur:
Bioss
Description:
The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2905R-A555)
Fournisseur:
Bioss
Description:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(MURRP514/14)
Fournisseur:
MURRAY, S & CO LTD
Description:
Dispensing pump is suitable for lotions, creams and gels.
UOM:
1 * 20 ST
Numéro de catalogue:
(BOSSBS-13070R-A488)
Fournisseur:
Bioss
Description:
The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.
UOM:
1 * 100 µl
Fournisseur:
Biotium
Description:
Recognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Fournisseur:
Biotium
Description:
Recognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Numéro de catalogue:
(663-0234)
Fournisseur:
VWR Collection
Description:
Conforme aux BPL, ce conductimètre portable est doté d'un boîtier solide IP 67 ainsi que d'une sortie USB étanche pour le connecter à un ordinateur. Il offre une résolution et une précision élevées pour vos mesures de terrain.
UOM:
1 * 1 SET
Fournisseur:
Biotium
Description:
Recognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein.The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Fournisseur:
Biotium
Description:
Recognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein.The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Fournisseur:
THERMO SAVANT EC
Description:
Vacuum pump flushing fluid, 1 l
Numéro de catalogue:
(444-0938)
Fournisseur:
GRANT INSTRUMENTS
Description:
Agitateur thermoshake compact avec vitesse et températures variables. Cet agitateur chauffant et refroidissant offre des fonctions de chauffage et de mélange simultanées ou indépendantes. Cette unité est idéale pour l'extraction de l'ADN/ARN, la préparation d'échantillons, les réactions enzymatiques et l'extraction de métabolites de matériaux cellulaires.
UOM:
1 * 1 ST
Fournisseur:
Binder
Description:
The KBF series is a proven specialist for reliable ICH stability tests in the pharmaceutical industry: the KBF masters all long-term tests, accelerated tests and stress tests. It fulfills all important ICH requirements, from precision to programming and documentation. With flexible water supply options for all installation locations. The units have a stainless-steel inner chamber and proven APT.line™ preheating chamber technology, feature a temperature range of 0 to +70 °C, and humidity range of 10 to 80% RH, the KBF consumes up to 40 % less energy than its predecessor. With optional light modules, the KBF can be converted into an ICH photostability chamber and a plant growth chamber.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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