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Masterflex®+L/S®+MasterSense™+Fill/Finish+Pump+System
Numéro de catalogue:
(BOSSBS-1764R-A555)
Fournisseur:
Bioss
Description:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0199R-FITC)
Fournisseur:
Bioss
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3830R-HRP)
Fournisseur:
Bioss
Description:
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1958R-A750)
Fournisseur:
Bioss
Description:
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4838R-A647)
Fournisseur:
Bioss
Description:
HE4 is a broad range protease inhibitor. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3939R-A680)
Fournisseur:
Bioss
Description:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6316R-A350)
Fournisseur:
Bioss
Description:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6316R-A555)
Fournisseur:
Bioss
Description:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11317R-A555)
Fournisseur:
Bioss
Description:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11317R-A488)
Fournisseur:
Bioss
Description:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4838R-FITC)
Fournisseur:
Bioss
Description:
HE4 is a broad range protease inhibitor. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12320R-A680)
Fournisseur:
Bioss
Description:
Defects in TCTN2 are the cause of Meckel syndrome type 8 (MKS8) [MIM:613885]. A disorder characterised by a combination of renal cysts and variably associated features including developmental anomalies of the central nervous system (typically encephalocele), hepatic ductal dysplasia and cysts, and polydactyly.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3939R-A555)
Fournisseur:
Bioss
Description:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6316R-FITC)
Fournisseur:
Bioss
Description:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6316R-A680)
Fournisseur:
Bioss
Description:
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11297R-CY7)
Fournisseur:
Bioss
Description:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
UOM:
1 * 100 µl
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