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Masterflex®+L/S®+MasterSense™+Fill/Finish+Pump+System
Numéro de catalogue:
(BOSSBS-12145R-A555)
Fournisseur:
Bioss
Description:
The CART gene encodes for a protein which has an important role in the regulation of appetite and body weight. The CART (cocaine- and amphetamine-regulated transcript) neuropeptide is an mRNA that changes in response to psychostimulant drug administration. Injection of CART peptides into the ventral tegmental area produces psychostimulant-like effects. CART localizes to areas of the central and peripheral nervous systems and is involved in feeding behavior when injected centrally. Expression of CART in the rat hypothalamus is modulated by nutritional status, and injection of synthetic CART peptide into the forebrain ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. Its identification in cell bodies and central terminals of vagal afferent neurons additionally suggests a role in brainstem mechanisms of meal termination and satiety.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2076R-A647)
Fournisseur:
Bioss
Description:
Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13370R-A647)
Fournisseur:
Bioss
Description:
The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2076R-FITC)
Fournisseur:
Bioss
Description:
Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2076R)
Fournisseur:
Bioss
Description:
Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9629R-FITC)
Fournisseur:
Bioss
Description:
Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
UOM:
1 * 100 µl
Fournisseur:
PFENNIG REINIGUNGSTECHNIK
Description:
Mop frame is suitable for use with all Pfennig mop heads: standard, professional, and universal.
Numéro de catalogue:
(BOSSBS-10085R-CY7)
Fournisseur:
Bioss
Description:
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1027R-CY5)
Fournisseur:
Bioss
Description:
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3944R-A555)
Fournisseur:
Bioss
Description:
GNG2 (Guanine nucleotide binding protein (G protein), gamma 2) is a member of the guanine nucleotide-binding proteins (G proteins) family. Heterotrimeric G proteins are involved as a modulator or transducer in various transmembrane signaling systems. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3081R-A488)
Fournisseur:
Bioss
Description:
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3081R-A350)
Fournisseur:
Bioss
Description:
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1251R-CY5)
Fournisseur:
Bioss
Description:
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7001R-A680)
Fournisseur:
Bioss
Description:
Tissue specificity; Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1251R-CY5.5)
Fournisseur:
Bioss
Description:
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
UOM:
1 * 100 µl
Fournisseur:
VWR Collection
Description:
Scalable, compliant chromatography software platform with multi-instrument control. OpenLAB CDS EZChrom Edition is part of the Agilent software suite OpenLAB for analytical laboratories and enterprise. Its multi-instrument control capabilities, scalability and compliance are ideal to fulfil the requirements of today's chromatography laboratories, and to optimise their efficiency. Central administration functions have been arranged in the OpenLAB Shared Services/Control Panel module while keeping the existing user-interface and workflows for the EZChrom Elite™ chromatography data system. Many exciting functions are now available, from the Result Package mode and Result Review/Result Sequence mode to the new Intelligent Reporting mode. OpenLAB CDS EZChrom Edition can be easily complemented by further software modules belonging to the OpenLAB software suite.
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