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Single-use+Pressure+Sensor
Numéro de catalogue:
(MMMA7100260622)
Fournisseur:
3M
Description:
For effective protection against a range of particulates, gases, and vapours, or combination hazards, use 3M™ filters DT series. Suitable for use with certain 3M™ half and full-face tight-fitting respirators in negative-pressure mode as well as 3M™ powered air respirator system PF-600E+ series.
UOM:
1 * 10 ST
New Product
Numéro de catalogue:
(BOSSBS-6124R-A750)
Fournisseur:
Bioss
Description:
Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0356R-CY3)
Fournisseur:
Bioss
Description:
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1370R-HRP)
Fournisseur:
Bioss
Description:
Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1370R-A350)
Fournisseur:
Bioss
Description:
Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1370R)
Fournisseur:
Bioss
Description:
Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. recognises the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B-lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates DYRK2, CHEK2, p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Binds DNA ends. Plays a role in replication-dependent histone mRNA degradation. Phosphorylation of DYRK2 in nucleus in response to genotoxic stress prevents its MDM2-mediated ubiquitination and subsequent proteasome degradation. Phosphorylates ATF2 which stimulates its function in DNA damage response.
UOM:
1 * 100 µl
Numéro de catalogue:
(620-2397)
Fournisseur:
TESTO
Description:
Ces sondes Smart Probes sont destinées à être utilisées avec des smartphones et des tablettes. Les utilisateurs peuvent lire les mesures au moyen de l'application Smart Probes de Testo installée sur leur périphérique. L'application vous permet de lire à distance les mesures transmises par six sondes Smart Probes et de documenter/consigner facilement les résultats. Utilisées avec des tubes de Pitot (non inclus), elles peuvent servir à déterminer la vitesse de l'air et le débit volumique.
UOM:
1 * 1 ST
Numéro de catalogue:
(391-0649)
Fournisseur:
Thermo Fisher Scientific
Description:
Microplate sealing tape consisting of pre-cut, pressure-sensitive sheets for sealing the surface of standard 96-well or 384-well microplates during incubation steps.
UOM:
1 * 100 ST
Numéro de catalogue:
(BOSSBS-6125R-A750)
Fournisseur:
Bioss
Description:
Component of the MRE11/RAD50/NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability.
UOM:
1 * 100 µl
Fournisseur:
iST Scientific Ltd
Description:
Transparent, non collant, film sensible à la pression pour plaques qPCR (96 ou 384 puits) et avec fluorescence connue.
Numéro de catalogue:
(BOSSBSM-0356M-A680)
Fournisseur:
Bioss
Description:
Digoxin is a beta blocker drug originally derived from the foxglove plant, <i>Digitalis lanata</i>. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalise some dysrhythmias (abnormal types of heartbeat).
UOM:
1 * 100 µl
Fournisseur:
Brady
Description:
This indoor marking film is an aqueous, inkjet printable, flexible, matte finish, pressure sensitive adhesive product that is designed to be used with the BradyJet™ J5000 colour label printer.
Numéro de catalogue:
(731-0750)
Fournisseur:
Thermo Fisher Scientific
Description:
Vinyl film with pressure sensitive acrylate adhesive. For application to plate top or bottom, to protect light sensitive samples.
UOM:
1 * 50 ST
Numéro de catalogue:
(181-0362)
Fournisseur:
EDWARDS HIGH VACUUM METTLER
Description:
These XDS series pumps are completely oil free, dry scroll and improved on their pumping speeds, combined with lower ultimate pressures, lower power consumption and lower noise. Gas ballast allows for pumping of condensable vapours including water, solvents, dilute acids and bases. It also feature the latest in tip seal technology giving significantly longer life between tip seal changes. Comes with integrated inverter drive with auto sensing voltage input delivers optimised pumping performance. The pumps are completely field serviceable.
UOM:
1 * 1 ST
Fournisseur:
VWR Chemicals
Description:
VWR® 4Å Molecular Sieve is a widely used adsorbent for many different applications. It exhibits high water adsorption capacity at low partial pressures and at temperatures up to 100°C. This molecular sieve is commonly used for drying of organic liquids (solvents, oils, gasolinea and other saturated hydrocarbons, air, liquid gases (propane, butane), as well as noble and other gases (H2, N2, He, Ar, etc.).
Fournisseur:
Sartorius
Description:
These smooth filter papers are made of refined pulp and linters with more than 95% alpha-cellulose content. The ash content of these filter papers is between 0,1 and 0,15%. They are used for routine analyses like clarification, determination of substances, but also as discs with a centre hole for technical applications. Grades with a wet burst resistance >30 kPa are referred to as wet-strengthened and are therefore suitable for pressure or vacuum filtration.
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 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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