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Solid+Phase+Extraction
Numéro de catalogue:
(KINE9753901)
Fournisseur:
KINEMATICA
Description:
This laboratory mill is characterised by a very robust design using solid milled parts and hardened components that have been designed for high wear and tear found with such processes as grinding of stones which can have a hardness of up to six on the Mohs scale. You will receive tried and tested Swiss quality.
UOM:
1 * 1 ST
Fournisseur:
VARIAN
Description:
Type de colonne: Colonne HPLC, PLRP-S, Seperation of synthetic peptides & recombinant peptides and proteins by reverse phase, Ø int.: 100,00 mm, Longueur: 300 mm, Taille de pore: 100 Å, Granulométrie: 8 µm
Fournisseur:
G-Biosciences
Description:
HOOK™ IgG biotinylation kits are designed for the biotinylation of IgG molecules by immobilising the IgG molecules on a solid support. Nickel chelating resin allows for the rapid removal of uncoupled biotin and therefore eliminates the need for further dialysis or desalting of the biotinylated antibody.
Numéro de catalogue:
(PRSI33-551)
Fournisseur:
ProSci Inc.
Description:
It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BOSSBS-6941R-A488)
Fournisseur:
Bioss
Description:
Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. The RAG complex also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. The introduction of DNA breaks by the RAG complex on one immunoglobulin allele induces ATM-dependent repositioning of the other allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. In addition to its endonuclease activity, RAG1 also acts as a E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H3. Histone H3 monoubiquitination is required for the joining step of V(D)J recombination.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6941R-A555)
Fournisseur:
Bioss
Description:
Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. The RAG complex also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. The introduction of DNA breaks by the RAG complex on one immunoglobulin allele induces ATM-dependent repositioning of the other allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. In addition to its endonuclease activity, RAG1 also acts as a E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H3. Histone H3 monoubiquitination is required for the joining step of V(D)J recombination.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6941R-CY3)
Fournisseur:
Bioss
Description:
Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends. The chromatin structure plays an essential role in the V(D)J recombination reactions and the presence of histone H3 trimethylated at 'Lys-4' (H3K4me3) stimulates both the nicking and haipinning steps. The RAG complex also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. The introduction of DNA breaks by the RAG complex on one immunoglobulin allele induces ATM-dependent repositioning of the other allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. In addition to its endonuclease activity, RAG1 also acts as a E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H3. Histone H3 monoubiquitination is required for the joining step of V(D)J recombination.
UOM:
1 * 100 µl
Fournisseur:
Cayman Chemical
Description:
Estriol ELISA kit is used for the quantification of estradiol in plasma and other sample matrices.
Fournisseur:
NASCO FORT ATKINSON
Description:
For collecting liquids, powders, or small solids from a horizontal flowing stream
Fournisseur:
Restek
Description:
High polar phase; biscyanopropyl cyanopropylphenyl polysiloxane, general-purpose columns for cis/trans FAMEs, dioxin isomers.
Fournisseur:
MULTIROIR
Description:
Ces caisses-palettes en polypropylène sont idéales pour le stockage, le transport et la préparation de marchandises et/ou de denrées alimentaires. Leur matériau leur confère des propriétés exceptionnelles en termes de résistance chimique, de résistance aux chocs et aux variations de température.
Numéro de catalogue:
(PRSI92-168)
Fournisseur:
ProSci Inc.
Description:
Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.
UOM:
1 * 50 µG
Numéro de catalogue:
(PHEN00F-4041-E0)
Fournisseur:
PHENOMENEX
Description:
Luna® C18 is a reversed phase column that provides a measurable improvement over many HPLC columns for two important chromatographic properties - resolution and peak shape.
UOM:
1 * 1 Pce
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(PHEN00F-4601-E0)
Fournisseur:
PHENOMENEX
Description:
Kinetex C18 are core-shell silica supported 100 Å columns with TMS endcapping for general reversed phase separations.
UOM:
1 * 1 Pce
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
Greiner Bio-One
Description:
En PS, sans couvercle. Un large éventail de microplaques à 96 puits est disponible avec de nombreux traitements de surface différents, un choix de profils de puits et un fond plein ou μClear®. Toutes les plaques sont exemptes de DNase, de RNase et d'ADN humain et apyrogènes.
Fournisseur:
PerkinElmer
Description:
Colonnes à usage général comportant une phase hautement polyvalente et extrêmement résistante, pour une longue durée de vie et des températures de fonctionnement élevées. Idéales pour l'analyse des échantillons pétrochimiques non polaires, par exemple pour l'analyse détaillée des hydrocarbures, les gaz d'hydrocarbures, les oxydes de pétrole, les hydrocarbures aromatiques, les cires et huiles de pétrole, les composés sulfurés, les mercaptans, le sulfure de carbone. Elles constituent également une excellente phase pour les solvants, produits chimiques, arômes, parfums, huiles essentielles, toxines de l'air, chlorofluorocarbones, pesticides et hydrocarbures.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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