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Numéro de catalogue: (BOSSBS-1820R-CY5.5)

Fournisseur:  Bioss
Description:   High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
UOM:  1 * 100 µl
Numéro de catalogue: (IMMRIR1373)

Fournisseur:  ImmunoReagents
Description:   ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  
UOM:  1 * 1 mg
Numéro de catalogue: (700-0876)

Fournisseur:  VWR Collection
Description:   Le plus petit de la série Maxi, le Maxi S Plus, convient à la séparation d’échantillons de haute qualité pouvant aller jusqu’à 160 échantillons par cycle. Avec ce système flexible, la taille du gel peut être divisée en deux, trois ou quatre sections en utilisant différentes positions de peigne. La taille du gel peut également être réduite en utilisant le peigne mural ou le système de barrage de coulage.
UOM:  1 * 1 ST

Fournisseur:  ImmunoReagents
Description:   ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  
UOM:  1 * 1 mg
Numéro de catalogue: (AGLS5188-8825)

Fournisseur:  AGILENT
Description:   The multiple affinity removal spin cartridge – Human Albumin/IgG is designed to remove two interfering high-abundant proteins from human samples (such as plasma, serum, urine or cerebrospinal fluid).
UOM:  1 * 1 ST

Fournisseur:  US Biological
Description:   Anti-HMGN3 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:  1 * 200 µl

Fournisseur:  Bioss
Description:   IGSF1 is a highly glycolylated immunoglobulin domain-containing protein. IGSF1 has been shown to act as a coreceptor in inhibin signaling, however, it does not appear to be a high-affinity inhibin receptor by itself. May reduce or inhibit activin A signaling and is believed to be necessary in the mediation of specific effects of inhibin B on activin-stimulated transcription. IGSF1 has been found to interact with several members of the ACVR family and possibly some members of the BMPR group. There are 3 known isoforms of IGSF1, with 1 and 2 likely being multi-pass membrane proteins. Isoform 3 is believed to be expressed as a secreted form. Expression is high in pancreas, testis and fetal liver, while heart, prostate and small intestine show only moderate expression. IGSF1 may be found at very low levels in brain, muscle, thymus, ovary, colon, fetal lung and fetal kidney. Isoform 3 has been detected in pituitary gland.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   IGSF1 is a highly glycolylated immunoglobulin domain-containing protein. IGSF1 has been shown to act as a coreceptor in inhibin signaling, however, it does not appear to be a high-affinity inhibin receptor by itself. May reduce or inhibit activin A signaling and is believed to be necessary in the mediation of specific effects of inhibin B on activin-stimulated transcription. IGSF1 has been found to interact with several members of the ACVR family and possibly some members of the BMPR group. There are 3 known isoforms of IGSF1, with 1 and 2 likely being multi-pass membrane proteins. Isoform 3 is believed to be expressed as a secreted form. Expression is high in pancreas, testis and fetal liver, while heart, prostate and small intestine show only moderate expression. IGSF1 may be found at very low levels in brain, muscle, thymus, ovary, colon, fetal lung and fetal kidney. Isoform 3 has been detected in pituitary gland.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-3635R-A488)

Fournisseur:  Bioss
Description:   The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12883R-A680)

Fournisseur:  Bioss
Description:   The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localisation of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-10288R-A750)

Fournisseur:  Bioss
Description:   Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream Signalling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7671R-A555)

Fournisseur:  Bioss
Description:   May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-15567R-FITC)

Fournisseur:  Bioss
Description:   This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1004R-A750)

Fournisseur:  Bioss
Description:   Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to Hydrolyse apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
UOM:  1 * 100 µl
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