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block+heaters+
Numéro de catalogue:
(BOSSBS-12215R-FITC)
Fournisseur:
Bioss
Description:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(A1288.0500)
Fournisseur:
PanReac AppliChem
Description:
Kolliphor® P 188 (Lutrol® F68, Pluronic® F-68, Synperonic® F68, Poloxamer 188)
UOM:
1 * 500 g
Numéro de catalogue:
(BOSSBS-1610R-A680)
Fournisseur:
Bioss
Description:
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1235R-CY5)
Fournisseur:
Bioss
Description:
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM:
1 * 100 µl
Fournisseur:
GRANT INSTRUMENTS
Description:
Bloc interchangeable, HC24N, Grant-bio, Pour: Microtubes 24×1,5 ml
Numéro de catalogue:
(BOSSBS-0534R-A488)
Fournisseur:
Bioss
Description:
P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.
UOM:
1 * 100 µl
Fournisseur:
Biotium
Description:
Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).
Fournisseur:
Biotium
Description:
Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).
Numéro de catalogue:
(BOSSBS-0534R-A680)
Fournisseur:
Bioss
Description:
P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.
UOM:
1 * 100 µl
Fournisseur:
3M
Description:
These earmuffs combine excellent protection with ultimate comfort. They are available as headband and helmet-mounted versions, offering a wide range of attenuation levels that meet the needs of the majority of industrial applications.
Numéro de catalogue:
(ENZOALX380100C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
A potent and specific nuclear export inhibitor. In addition to antifungal and antibacterial activities, blocks the cell cycle and is a potent anti-tumor agent.
UOM:
1 * 1 EA
New Product
Fournisseur:
VWR Collection
Description:
These jumbo size display thermometers are suitable for monitoring freezers, water baths, heating blocks, incubators and refrigerators. A bottle insulates the sensor from transient temperature changes when the refrigerator door is opened. Solution is GRAS (Generally Recognised As Safe) by the FDA (Food and Drug Administration).
Fournisseur:
GRANT INSTRUMENTS
Description:
Bloc de rechange pour PSC96, Pour: Microplaque 96 puits
Fournisseur:
Cytiva (Formerly Pall Lab)
Description:
Le collecteur de vide pour plaques multi-puits est un collecteur en aluminium anodisé conçu et optimisé pour la filtration par le vide des plaques de filtration multi-puits AcroPrep™, AcroPrep Advance et AcroWell™.
Fournisseur:
VWR Collection
Description:
Ces tubes à centrifuger étanches sont fabriqués à partir de PP ambré foncé et protègent les échantillons sensibles à la lumière en bloquant les rayons UV.
Fournisseur:
Biowest
Description:
Feline serum is the liquid fraction of whole blood that is collected after the blood is allowed to clot; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances. Feline serum is used as a blocking agent in immunoassays and controls.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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