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cell+culture+flasks
Numéro de catalogue:
(BOSSBS-3148R-HRP)
Fournisseur:
Bioss
Description:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3148R-FITC)
Fournisseur:
Bioss
Description:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BNUM0942-50)
Fournisseur:
Biotium
Description:
Recognizes a protein of 40-45 kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.
UOM:
1 * 50 µl
Numéro de catalogue:
(BOSSBS-5120R-A488)
Fournisseur:
Bioss
Description:
Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes and the endoplasmic reticulum.
UOM:
1 * 100 µl
Numéro de catalogue:
(80101.)
Fournisseur:
Biotium
Description:
Sulforhodamine 101 has a longer absorption wavelength than does sulforhodamine B. Like sulforhodamine B and G, in addition to their potential use in cancer drug screening, these fluorescent dyes have been primarily used as polar tracers for the studies of neuronal cell morphology and cell-cell communication.
UOM:
1 * 500 mg
Numéro de catalogue:
(BOSSBS-0756R-CY7)
Fournisseur:
Bioss
Description:
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0756R-CY5)
Fournisseur:
Bioss
Description:
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9246R-CY7)
Fournisseur:
Bioss
Description:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3121R-A488)
Fournisseur:
Bioss
Description:
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1460R-CY3)
Fournisseur:
Bioss
Description:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1460R-A488)
Fournisseur:
Bioss
Description:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3121R)
Fournisseur:
Bioss
Description:
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10662R-A750)
Fournisseur:
Bioss
Description:
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP Signalling cascade. Required for GDF2/BMP9 Signalling through SMAD1 in endothelial cells and modulates TGF-beta1 Signalling through SMAD3.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5767R-CY3)
Fournisseur:
Bioss
Description:
Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7103R-A750)
Fournisseur:
Bioss
Description:
THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalises with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5745R-CY5.5)
Fournisseur:
Bioss
Description:
CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
UOM:
1 * 100 µl
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