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Fournisseur:  Biotium
Description:   CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Fournisseur:  Biotium
Description:   CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
UOM:  1 * 50 µl

Fournisseur:  Bioss
Description:   Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2604R-CY5.5)

Fournisseur:  Bioss
Description:   Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2604R-CY3)

Fournisseur:  Bioss
Description:   Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2177R-CY3)

Fournisseur:  Bioss
Description:   Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity). Enhances migration and invasion of cancer cells through WNT5A signaling.
UOM:  1 * 100 µl
Fournisseur:  Biotium
Description:   This MAb reacts with 9-O-acetylated disialosyl group linked to the glycoprotein CD60w. CDw60 is a carbohydrate antigen present on gangliosides, platelets and a subset of CD4 , CD8 peripheral T-cells, but not on B-cells, monocytes or granulocytes. CDw60 is involved in the co-stimulation of T-cells.

Fournisseur:  Bioss
Description:   May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6030R-A647)

Fournisseur:  Bioss
Description:   Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6030R-A350)

Fournisseur:  Bioss
Description:   Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-2521R-CY7)

Fournisseur:  Bioss
Description:   Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-5499R)

Fournisseur:  Bioss
Description:   MyoD1 belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. Myod1 is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis.
UOM:  1 * 100 µl
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