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Anticorps
Numéro de catalogue:
(USBII7660-17E)
Fournisseur:
US Biological
Description:
Anti-INS Mouse Monoclonal Antibody [clone: 5E679]
UOM:
1 * 500 µG
Numéro de catalogue:
(USBII7661-01P)
Fournisseur:
US Biological
Description:
Anti-Insulin-Like Growth Factor I Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5347R-A350)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9134R-A647)
Fournisseur:
Bioss
Description:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-7 (ankyrin repeat and SOCS box-containing 7) is a 318 amino acid protein that contains one SOCS box domain and seven ANK repeats and belongs to the ASB family. Existing as multiple alternatively spliced isoforms, ASB-7 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins.
UOM:
1 * 100 µl
Numéro de catalogue:
(USBI044240-APC)
Fournisseur:
US Biological
Description:
Anti-ZNF451 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI044239-APC)
Fournisseur:
US Biological
Description:
Anti-ZNF443 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI037602-PE)
Fournisseur:
US Biological
Description:
Anti-KRR1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Numéro de catalogue:
(BOSSBS-10153R-CY7)
Fournisseur:
Bioss
Description:
Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.Belongs to the SECTM family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-10153R-HRP)
Fournisseur:
Bioss
Description:
Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.Belongs to the SECTM family.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12261R-FITC)
Fournisseur:
Bioss
Description:
RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these also stain stromal cells in the thymus.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2374R-FITC)
Fournisseur:
Bioss
Description:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6133R-CY5.5)
Fournisseur:
Bioss
Description:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13666R-A488)
Fournisseur:
Bioss
Description:
STAC2
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2374R-PE)
Fournisseur:
Bioss
Description:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6133R-FITC)
Fournisseur:
Bioss
Description:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0932R-CY5.5)
Fournisseur:
Bioss
Description:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
UOM:
1 * 100 µl
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