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Anticorps
Numéro de catalogue:
(AGRIAS122118)
Fournisseur:
Agrisera
Description:
Anti-SNE18 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Numéro de catalogue:
(BOSSBS-6596R-CY7)
Fournisseur:
Bioss
Description:
STMN3 belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8575R-A488)
Fournisseur:
Bioss
Description:
FSIP1 is a 581 amino acid protein that is expressed in airway epithelium. A member of the FSIP1 family, FSIP1 is encoded by a gene that maps to human chromosome 15q14 and mouse chromosome 2 E5. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11936R-CY7)
Fournisseur:
Bioss
Description:
Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8576R-A350)
Fournisseur:
Bioss
Description:
PLEKHJ1 is a 149 amino acid phosphoprotein that contains one PH (pleckstrin homology) domain and is expressed in testis and liver. The gene that encodes PLEKHJ1 maps to human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 contains the greatest gene density of the human chromosomes and is the genetic home for a number of immunoglobulin superfamily members, including killer cell and leukocyte Ig-like receptors, ICAMs, the CEACAM and PSG families, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes are also linked to chromosome 19.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4914R-A350)
Fournisseur:
Bioss
Description:
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6750R-A680)
Fournisseur:
Bioss
Description:
WD repeat containing proteins, such as WDR16, play crucial roles in a wide range of physiologic functions, including signal transduction, RNA processing, remodeling the cytoskeleton, regulation of vesicular traffic, and cell division.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5103R-A350)
Fournisseur:
Bioss
Description:
This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production. It probably has a preference for proteins phosphorylated on Ser and/or Thr residues compared to phosphorylation on Tyr residues. It is likely to be involved in the regulation of insulin secretion in pancreatic beta cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8680R-A750)
Fournisseur:
Bioss
Description:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8680R-CY7)
Fournisseur:
Bioss
Description:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15404R-CY7)
Fournisseur:
Bioss
Description:
HAGH.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9221R-A647)
Fournisseur:
Bioss
Description:
The specific function of C1orf177 is not yet known.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9291R-A555)
Fournisseur:
Bioss
Description:
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9290R-CY5.5)
Fournisseur:
Bioss
Description:
PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52% identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.3, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes. Participating in E2-dependent, E3 ubiquitin-protein ligase activity, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, such as UBE2D2, in vitro.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12419R-HRP)
Fournisseur:
Bioss
Description:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12478R-CY7)
Fournisseur:
Bioss
Description:
The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.
UOM:
1 * 100 µl
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