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Protéines et Peptides
Fournisseur:
Shenandoah Biotechnology
Description:
Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.
Fournisseur:
Shenandoah Biotechnology
Description:
Interferon-alpha 2a (IFN-α 2a) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α 2a. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α 2a variant differs from IFN-α 2b by one amino acid.
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1α and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells and is aberrantly expressed in Hodgkin lymphoma cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells.
Fournisseur:
Shenandoah Biotechnology
Description:
Interleukin 35 (IL-35) is a member of the IL-12 cytokine family and is produced by regulatory T cells (Tregs). IL-35 is a heterodimeric cytokine that is comprised of the p35 subunit (IL-12A) and the Epstein-Barr virus induced gene 3 subunit (EBI3/IL-27B). IL-35 binds the IL-12Rbeta2/gp130 hetero- and homodimers to activate STAT1 and STAT4 signaling. IL-35 functions as a suppressor of immune cell inflammatory responses.
Fournisseur:
Shenandoah Biotechnology
Description:
Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).
Fournisseur:
Shenandoah Biotechnology
Description:
Indian hedgehog (IHH) is an essential signaling factor that is secreted in the gut, cartilage, and bone during embryonic development. IHH acts through the patched (PTC) receptor to induce transcriptional changes important for bone and cartilage development. IHH also induces the expression of parathyroid hormone-related peptide (PTHrP), which in turn mediates IHH activity during chondrocyte differentiation, forming a negative feedback loop.
Numéro de catalogue:
(PRSI91-815)
Fournisseur:
ProSci Inc.
Description:
CD320 antigen is also known as 8D6 antigen，FDC-signaling molecule 8D6，Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6557P)
Fournisseur:
ProSci Inc.
Description:
AFAP1 peptide is used for blocking the activity of AFAP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6553P)
Fournisseur:
ProSci Inc.
Description:
SPATA4 peptide is used for blocking the activity of SPATA4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6595P)
Fournisseur:
ProSci Inc.
Description:
CD33 peptide is used for blocking the activity of CD33 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6593P)
Fournisseur:
ProSci Inc.
Description:
MS4A6A peptide is used for blocking the activity of MS4A6A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6555P)
Fournisseur:
ProSci Inc.
Description:
SPATA6 peptide is used for blocking the activity of SPATA6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7179P)
Fournisseur:
ProSci Inc.
Description:
16 amino acids near the carboxy terminus of human TRPV1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7187P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the carboxy terminus of human FOXP3.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7199P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the carboxy terminus of human PDGF-B.
UOM:
1 * 50 µG
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