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Bioss
Numéro de catalogue:
(BOSSBS-11462R-CY3)
Fournisseur:
Bioss
Description:
NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11462R-A555)
Fournisseur:
Bioss
Description:
NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumor lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2014R-CY3)
Fournisseur:
Bioss
Description:
Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0319R-CY5.5)
Fournisseur:
Bioss
Description:
Anti-E1 glycoprotein Rabbit Polyclonal Antibody (Cy5.5®)
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0318R-HRP)
Fournisseur:
Bioss
Description:
PADI4 (peptidyl arginine deiminase, type IV) catalyzes the deimination of arginine residues of proteins. Down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. subcellular location at cytoplasmic granules. Belongs to the protein arginine deiminase family. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13164R-A350)
Fournisseur:
Bioss
Description:
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5755R-A350)
Fournisseur:
Bioss
Description:
Component of the cytoplasmic fibrils of the nuclear pore complex implicated in nuclear protein import. Its N-terminus is involved in activation of oncogenic kinases. Plays a role in the mitotic spindle checkpoint.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5754R-FITC)
Fournisseur:
Bioss
Description:
SP17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5754R-CY5)
Fournisseur:
Bioss
Description:
SP17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2014R-FITC)
Fournisseur:
Bioss
Description:
Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2014R-CY7)
Fournisseur:
Bioss
Description:
Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0492R-A750)
Fournisseur:
Bioss
Description:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13054R-CY5)
Fournisseur:
Bioss
Description:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0200R-CY7)
Fournisseur:
Bioss
Description:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0332R-A750)
Fournisseur:
Bioss
Description:
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0418R-CY3)
Fournisseur:
Bioss
Description:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
UOM:
1 * 100 µl
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